Table 1 Sensitivity/Specificity comparison of variational EM algorithm with MCMC algorithm
True NRAF | Median depth | Sensitivity | Specificity | ||
|---|---|---|---|---|---|
MCMC | Variational | MCMC | Variational | ||
0.1% | 39 | 0.00 | 0.00 | 1.00 | 1.00 |
408 | 0.00 | 0.07 | 1.00 | 1.00 | |
4129 | 0.14 | 0.29 | 1.00 | 1.00 | |
41449 | 0.86 | 1.00 | 0.97 | 1.00 | |
0.3% | 36 | 0.00 | 0.00 | 1.00 | 1.00 |
410 | 0.00 | 0.00 | 1.00 | 1.00 | |
4156 | 1.00 | 1.00 | 0.99 | 0.98 | |
41472 | 1.00 | 0.93 | 0.85 | 0.91 | |
1.0% | 53 | 0.00 | 0.00 | 1.00 | 1.00 |
535 | 0.21 | 0.29 | 1.00 | 1.00 | |
5584 | 1.00 | 1.00 | 0.98 | 0.98 | |
55489 | 1.00 | 0.93 | 0.87 | 0.95 | |
10.0% | 22 | 0.00 | 0.57 | 1.00 | 1.00 |
260 | 1.00 | 1.00 | 1.00 | 1.00 | |
2718 | 1.00 | 1.00 | 1.00 | 1.00 | |
26959 | 1.00 | 1.00 | 1.00 | 1.00 | |
100.0% | 27 | 1.00 | 1.00 | 1.00 | 1.00 |
298 | 1.00 | 1.00 | 1.00 | 1.00 | |
3089 | 1.00 | 1.00 | 1.00 | 1.00 | |
30590 | 1.00 | 1.00 | 1.00 | 1.00 | |