Table 4 The number of identified miRNA sponge interactions and experimentally validated miRNA sponge interactions under different parameter settings
From: Identifying miRNA sponge modules using biclustering and regulatory scores
Parameter settings of miRSM | #Interactions | Validated miRNA sponge interactions | #Validated interactions |
|---|---|---|---|
a = 0.5, b = 0.5, s = -0.3 | 577544 | SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN | 5 |
a = 0.5, b = 0.5, s = -0.25 | 2033124 | AFF1:PTEN, ZEB2:PTEN, SERINC1:PTEN, MBNL1:PTEN, LRCH1:PTEN, KLF6:PTEN, FN1: VCAN | 7 |
a = 0.5, b = 0.5, s = -0.35 | 61161 | / | 0 |
a = 0.5, b = 0.5, s = -0.4 | 1041 | / | 0 |
a = 0.5, b = 0.5, s = -0.45 | 84 | / | 0 |
a = 0.4, b = 0.6, s = -0.3 | 17972 | LRCH1:PTEN, KLF6:PTEN | 2 |
a = 0.45, b = 0.55, s = -0.3 | 169617 | SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN | 5 |
a = 0.55, b = 0.45, s = -0.3 | 1228533 | SERINC1:PTEN, LRCH1:PTEN, KLF6:PTEN, ZEB2:PTEN, MBNL1:PTEN | 5 |
a = 0.6, b = 0.4, s = -0.3 | 2029912 | AFF1:PTEN, ZEB2:PTEN, SERINC1:PTEN, MBNL1:PTEN, LRCH1:PTEN, KLF6:PTEN, FN1:VCAN | 7 |