Table 6 Top 10 features in inactive structures among all ePKs, PTKs, and CMGCs
From: Classifying kinase conformations using a machine learning approach
ePK features | PKA positions | TK features | PKA positions | CMGC features | PKA positions |
|---|---|---|---|---|---|
χ1_121 | 168 | χ1_166 | 211 | Pd_217-220 | 268–271 |
χ1_64 | 110 | χ1_94 | 141 | Pd_56-59 | 102–105 |
χ1_79 | 125 | χ1_197 | 242 | Pd_157-160 | 202–205 |
χ1_142 | 189 | χ1_26 | 68 | Pd_202-205 | 247–250 |
χ1_100 | 147 | χ1_150 | 195 | Pd_219-222 | 270–273 |
χ1_218 | 269 | χ1_235 | 291 | Pd_229-232 | 280–283 |
χ1_29 | 71 | χ1_187 | 232 | Pd_109-112 | 156–159 |
χ1_132 | 179 | χ1_160 | 205 | Pd_95-98 | 142–145 |
χ1_156 | 201 | χ1_147 | N/A | Pd_199-202 | 244–247 |
χ1_131 | 178 | χ1_52 | 98 | Pd_85-88 | 131–134 |