Table 3 The survival time prediction performance (p-value and hazard ratio) for the top 5, top 10 and top 15 significant genes based on concordance index: DEA, dwgLASSO with no prior biological knowledge incorporated: dwgLASSO (no prior), KDDN, and dwgLASSO with prior biological knowledge incorporated: dwgLASSO (prior)

DEA

0.0073

1.851

2.00E-03

2.037

4.00E-04

2.274

dwgLASSO (no prior)

0.0066

1.864

3.10E-04

2.316

4.60E-06

2.969

KDDN

0.0022

2.028

7.46E-07

3.304

8.04E-06

2.889

dwgLASSO (prior)

0 . 0 0 1 3

2 . 1 0 4

7 . 0 1 E − 0 7

3 . 3 2 5

9 . 3 7 E − 0 7

3 . 2 5