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Table 2 Computational time and peak memory usage of MARV by varying sample size, chromosomal size and number of phenotypes

From: MARV: a tool for genome-wide multi-phenotype analysis of rare variants

Number of phenotypes (number of fitted models)

Chr 1 (249 Mbp)

Chr 22 (35 Mbp)

N = 2,405

h:min:s (memory)

h:min:s (memory)

2 (3)

4:06:54 (215 MB)

00:38:04 (260 MB)

4 (15)

3:51:23 (215 MB)

00:38:37 (260 MB)

8 (63)

5:07:11 (215 MB)

00:55:58 (260 MB)

N = 4,809

h:min:s (memory)

h:min:s (memory)

2 (3)

14:47:34 (780 MB)

02:26:00 (500 MB)

4 (15)

13:40:11 (780 MB)

02:26:10 (600 MB)

8 (63)

17:26:08 (780 MB)

03:03:00 (600 MB)