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Table 2 Functional annotation of prioritized proteins

From: VacSol: a high throughput in silico pipeline to predict potential therapeutic targets in prokaryotic pathogens using subtractive reverse vaccinology

Protein ID (VacSol)

Bacterial protein

Gene symbol (NCBI)

Molecular weight kDa (ExPASy)

Molecular function (UNIPROT)

Domains (Interpro Scan)

Trans-membrane Helices

3

Iron(III) dicitrate transport protein (FecA)

HP1400

94.827

Receptor activity

TonB-dependent receptor & plug domain

0

285

Flagellin A (FlaA)

HP0601

53.287

Cell motility, Signal transduction and structural molecule activity

Flagellin, Flagellin_D0/D1, Flagellin_hook_IN_motif

0

534

Putative beta-lactamase

HP1098

31.594

Beta-lactamase activity

Sel1-like, TPRlike_ helical_dom, TPR_2

0

825

Iron(III) dicitrate transport protein (FecA)

HP0807

88.946

Receptor activity

TonB-dependent receptor & plug domain

0

837

Flagellin B (FlaB)

HP0115

53.882

Structural molecule activity

Flagellin, Flagellin_D0/D1

0

907

Toxin-like outer membrane protein

HP0289

311.288

Not defined

Autotransport_beta& Vacuolating_cytot oxin_put

1

995

Toxin-like outer membrane protein

HP0922

274.563

Not defined

VacA2 (motif), Autotransporte_beta, PbH1

0

982

Beta-lactamase HcpA

HP0211

27.366

Peptidoglycan, cell wall synthesis

Sel1-like, TPRlike_helical_dom

0

1184

Toxin-like outer membrane protein

HP0610

212.964

Not defined

Vacuolating cytotoxin putative & Autotransporter beta domain

0

1359

Iron(III) dicitrate transport protein (FecA)

HP0686

87.698

Receptor activity

TonB-dependent receptor, betabarrel, plug domain

0