Fig. 2

Reference and predicted PPI networks in relation with the inferred homology network of autophagy in P. anserina. The figure illustrates the relation of each reference network with the predicted network. This hybrid network is a combination of different network types: it comprises both reference PPI networks, the predicted PPI network and the homology network which combines each of the PPI networks. All proteins from human (blue nodes) and yeast (green nodes) and their corresponding interactions used for the P. anserina PPI network (red nodes and edges) are shown. Homologous relationships between two proteins are depicted as dotted lines