AnkPlex: algorithmic structure for refinement of near-native ankyrin-protein docking

BMC Bioinformatics

Table 5 Comparison of performances of AnkPlex with single learning method and ZDOCK program^a

Method	Number of TP docking poses (rank)
Method	C₁	C₂	C₃	C₄	C₅	C₆	C₇	U₁	U₂
2Kp(ZDOCK)	0 (13)	1 (10)	6 (1)	7 (1)	1 (10)	1 (10)	8 (1)	0 (14)	0 (104)
OLM_DT (ABEHIJ_g56)	1 (4)	1 (4)	8 (1)	7 (1)	0 (14)	2 (1)	7 (1)	0 (13)	0 (160)
OLM_LG (CDFGHJ_g30)	2 (1)	1 (3)	8 (1)	10 (1)	1 (9)	0 (19)	7 (1)	1 (6)	1 (5)
AnkPlex	2 (1)	1 (3)	8 (1)	10 (1)	1 (9)	3 (2)	7 (1)	1 (6)	1 (5)

^aThe number of TP docking poses is the summation of the TP docking poses found in 10 top-ranking poses, where the maximum and the minimum are 10 and 0, respectively. The rank is denoted by the order in which the first TP docking poses are found. For example, on C₆, AnkPlex yields three TP docking poses on the top 10 ranking poses, and the orders of the three TP docking poses are 2, 8, and 9. Thus, the rank of AnkPlex on C₆ is 2

ISSN: 1471-2105