Fig. 9
From: Power analysis for RNA-Seq differential expression studies
False positive error rate plot for both Wald test and LRT with unequal dispersion parameters. False positive error rate was calculated for both Wald test (solid line) and LRT (dashed line) following a chi-square distribution with 1 degree of freedom at 3 different mean expression levels. The nominal false positive error rate control level for the empirical parametric test is shown in purple line (α=0.001). Both tests have inflated false positive error rates