Fig. 1
From: Simple adjustment of the sequence weight algorithm remarkably enhances PSI-BLAST performance
Examples showing the sequence weight calculation of PSI-BLAST and PSI-BLASTexB. a Sequence weights (shown on the right side) of all positions in the MSA were calculated from a single block covering the whole alignment. b PSI-BLAST divided the MSA into three blocks (blue, orange, and green) and calculated sequence weights for each block. Sequence weights calculated from the blocks are shown on the right side with the same color. For the orange block that is one aa long, PSI-BLASTexB extends the block such that the block width becomes MBW (red block). Weights calculated from the red block are also shown. See Methods for detailed procedures. “seq7” has no amino acid at position 23. For that reason, the sequence weights of other sequences are calculated ignoring “seq7” at the position