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Fig. 5 | BMC Bioinformatics

Fig. 5

From: AGeNNT: annotation of enzyme families by means of refined neighborhood networks

Fig. 5

rGNN of IPR007115 (6-pyruvoyl tetrahydropterin synthase/QueD family protein). This rGNN (named rGNN_7115_150) contains all nodes that represent more than 150 sequences. Dominating are cluster-nodes 65 (PTPS-I enzymes), 71 (PTPS-II enzymes), and 62 (PTPS-IV enzymes). Dominating Pfam-nodes are related to queosine biosynthesis (QueC, QueE, and QueF). The GNs of PTPS-II enzymes (cluster 71) and of PTPS-III enzymes consist of not more than two Pfam-nodes. The GNs of PTPS-IV enzymes contain FolE2; FolE belongs to the GN of cluster-nodes 5, 56, and 71

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