Skip to main content

Table 2 Comparison of haplotype frequencies using distance\( d \), maximal absolute difference between frequencies \( \textcolor[rgb]{1,0,0}{\backslash}\textcolor[rgb]{1,0,0}{\mathrm{increment}} \), and first rank with a relative deviation larger than 0.05, \( \rho \)

From: Hapl-o-Mat: open-source software for HLA haplotype frequency estimation from ambiguous and heterogeneous data

Data

Remark

\( d \)

\( \triangle \)

\( \rho \)

First artificial population

Integer-valued genotype numbers

\( 1.3\times {10}^{-4} \)

\( 9.04\times {10}^{-7} \)

None

Integer-valued genotype numbers and NMDP codes

\( 0.11\pm 0.02 \)

\( \left(4\pm 1\right)\times {10}^{-3} \)

\( 14\pm 6 \)

Second artificial population

Hapl-o-Mat – Population

\( 0.200 \)

\( 3.1\times {10}^{-3} \)

\( 1 \)

Arlequin – Population

\( 0.202 \)

\( 3.2\times {10}^{-3} \)

\( 1 \)

Arlequin – Hapl-o-Mat

\( 0.027 \)

\( 2.2\times {10}^{-4} \)

\( 106 \)

Real genotype data

Hapl-o-Mat – Arlequin

\( 0.072\pm 0.002 \)

\( \left(9\pm 2\right)\times {10}^{-4} \)

\( 41\pm 23 \)

  1. The observables were computed on basis of original and estimated haplotype frequencies. For the first artificial population, where we compared Hapl-o-Mat to population data, the column “Remark” indicates details of construction. For the other two genotype data sets, it indicates the sets of haplotype frequencies that are compared to each other, e.g. “Hapl-o-Mat – population” means haplotype frequencies obtained from Hapl-o-Mat were compared to original population haplotype frequencies