Table 2 Demographic, clinical and pathologic features of colorectal cancers in the network analysis dataset by tumor location
From: Biomarker correlation network in colorectal carcinoma by tumor anatomic location
|  | Total (n = 1380) | Proximal colon cancer (n = 690) | Distal colorectal cancer (n = 690) | P valuea |
|---|---|---|---|---|
Age, mean (SD) | 69.9 (8.6) | 70.0 (8.8) | 69.7 (8.5) | 0.56 |
Sex | ||||
 Female | 758 (54.9%) | 379 (54.9%) | 379 (54.9%) | 0.99 |
 Male | 622 (45.1%) | 311 (45.1%) | 311 (45.1%) | |
Tumor location | ||||
 Cecum | 253 (18.3%) | 253 (36.7%) | 0 (0%) | <0.0001 |
 Ascending colon | 303 (22.0%) | 303 (43.9%) | 0 (0%) | |
 Hepatic flexure | 45 (3.3%) | 45 (6.5%) | 0 (0%) | |
 Transverse colon | 89 (6.4%) | 89 (12.9%) | 0 (0%) | |
 Splenic flexure | 31 (2.2%) | 0 (0%) | 31 (4.5%) | |
 Descending colon | 66 (4.8%) | 0 (0%) | 66 (9.6%) | |
 Sigmoid colon | 296 (21.4%) | 0 (0%) | 296 (42.9%) | |
 Rectosigmoid junction | 100 (7.2%) | 0 (0%) | 100 (14.5%) | |
 Rectum | 197 (14.3%) | 0 (0%) | 197 (28.6%) | |
TNM Stage | ||||
 I | 324 (26.2%) | 146 (22.9%) | 178 (29.7%) | 0.002 |
 II | 404 (32.7%) | 232 (36.4%) | 172 (28.7%) | |
 III | 332 (26.8%) | 159 (24.9%) | 173 (28.9%) | |
 IV | 177 (14.3%) | 101 (15.8%) | 76 (12.7%) | |
Tumor differentiation | ||||
 Well to moderate | 1231 (89.2%) | 577 (83.6%) | 654 (94.8%) | <0.0001 |
 Poor | 149 (10.8%) | 113 (16.4%) | 36 (5.2%) | |
Family history of colorectal cancer in first-degree relative(s) | ||||
 No | 1074 (78.4%) | 532 (77.9%) | 542 (78.9%) | 0.65 |
 Yes | 296 (21.6%) | 151 (22.1%) | 145 (21.1%) | |