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Table 4 Markers with differential connectivity by tumor location based on Cook’s distance among highly-connected markersa

From: Biomarker correlation network in colorectal carcinoma by tumor anatomic location

Highly-connected markersa Degree centrality Degree in proximal colon cancer Degree in distal colorectal cancer Cook’s distance
MSI 0.45 21 9 0.12
IGF2 0.38 18 9 0.028
CRABP1 0.38 16 8 0.015
CACNA1G 0.45 18 10 0.0071
TIL 0.43 18 10 0.0071
  1. aHighly-connected markers which were at or above the 80th percentile of the degree distribution in the colorectal cancer network. The table shows markers with Cook’s distance higher than 0.005
  2. MSI microsatellite instability, TIL tumor infiltrating lymphocytes