Biomarker correlation network in colorectal carcinoma by tumor anatomic location

BMC Bioinformatics

Table 4 Markers with differential connectivity by tumor location based on Cook’s distance among highly-connected markers^a

Highly-connected markers^a	Degree centrality	Degree in proximal colon cancer	Degree in distal colorectal cancer	Cook’s distance
MSI	0.45	21	9	0.12
IGF2	0.38	18	9	0.028
CRABP1	0.38	16	8	0.015
CACNA1G	0.45	18	10	0.0071
TIL	0.43	18	10	0.0071

^aHighly-connected markers which were at or above the 80th percentile of the degree distribution in the colorectal cancer network. The table shows markers with Cook’s distance higher than 0.005
MSI microsatellite instability, TIL tumor infiltrating lymphocytes

ISSN: 1471-2105