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Table 2 The performance comparison between PVAAS and ISVASE

From: ISVASE: identification of sequence variant associated with splicing event using RNA-seq data

Data

Method

Precision

Consistency

PVAAS test data

PVAAS

0.00(0/8)

-

ISVASE(novel)

0.50(7/14)

-

ISVASE(all)

0.75(129/172)

-

Control1(SRR388226)

PVAAS

0.20(12/61)

0.46(28/61)

ISVASE(novel)

0.40(54/134)

0.65(87/134)

ISVASE(all)

0.83(2138/2577)

0.82(2105/2577)

Control1(SRR388227)

PVAAS

0.14(9/63)

0.44(28/63)

ISVASE(novel)

0.42(50/120)

0.73(87/120)

ISVASE(all)

0.83(2130/2557)

0.82(2105/2557)

PVAAS

0.07(2/28)

-

Control(common)

ISVASE(novel)

0.41(36/87)

-

ISVASE(all)

0.85(1788/2105)

-

Knockdown1(SRR388228)

PVAAS

0.19(18/93)

0.33(31/93)

ISVASE(novel)

0.44(83/187)

0.64(119/187)

ISVASE(all)

0.83(2250/2710)

0.85(2298/2710)

Knockdown2(SRR388229)

PVAAS

0.27(24/89)

0.35(31/89)

ISVASE(novel)

0.43(73/168)

0.71(119/168)

ISVASE(all)

0.83(2293/2760)

0.83(2298/2760)

Knockdown(common)

PVAAS

0.26(8/31)

-

ISVASE(novel)

0.46(55/119)

-

ISVASE(all)

0.85(1951/2298)

-

  1. Precision known SVASE/total SVASE, known SVASE defined as SVASE existed in dbSNP, Consistency common SVASE/total SVASE, common SVASE means the SVASE identified in both repeat samples