Fig. 1

Computational bioinformatics workflows are often deployed to deal with the data processing bottleneck. A typical workflow consists of a series of linked steps that transform raw input (e.g. a fastq file produced as a result of NGS data) into meaningful or interpretable output (e.g. variant calls). Typically, these steps are performed by specific tools developed to tackle a particular functional aspect of genomic sequence analysis. Workflows can have variable number of steps depending on the type of analysis performed, hence can be simple or complex