Table 1 Comparison of VISA and VISMapper using four datasets generated with the IS generator program from the the VISMapper website (https://visa.pharmacy.wsu.edu/bioinformatics/random_site_generator.html)
From: VISMapper: ultra-fast exhaustive cartography of viral insertion sites for gene therapy
Dataset | Input size (reads) | Insertion sites | Performance | VISA | VISMapper |
|---|---|---|---|---|---|
Input 1 | Runtime | ~72 h | ~60 s | ||
100,000 | 100,000 | IS detected | 99,694 | 99.793 | |
Total sequences mapped | 99,694 | 99,881 | |||
Input 2 | Runtime | ~72 h | ~60 s | ||
50,000 | 50,000 | IS detected | 49,854 | 49,897 | |
Total sequences mapped | 49,855 | 49,936 | |||
Input 3 | Runtime | ~72 h | ~30 s | ||
10,000 | 10,000 | IS detected | 9992 | 9969 | |
Total sequences mapped | 9995 | 9981 | |||
Input 4 | Runtime | ~5 h | ~30 s | ||
1000 | 1000 | IS detected | 906 | 929 | |
Total sequences mapped | 906 | 930 |