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Table 3 Normalized kernel weights with an extra positive definite, unit-diagonal, random valued kernel matrix

From: VB-MK-LMF: fusion of drugs, targets and interactions using variational Bayesian multiple kernel logistic matrix factorization

 

MrgRbf

MrgTan

McsRbf

McsTan

Orig

Random

Nuclear Receptor

0.175

0.176

0.175

0.175

0.175

0.123

GPCR

0.173

0.173

0.172

0.172

0.172

0.138

Ion Channel

0.176

0.176

0.176

0.176

0.176

0.120

Enzyme

0.176

0.176

0.176

0.176

0.176

0.119

 

-

2D

3D

ECFP

Random

Kinase

-

0.300

0.283

0.398

0.019

  1. The number of latent factors was not altered in this experiment. Setting the number of latent factors to I (the rank of the kernel matrix) zeroes out the weight of the random kernel
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BMC Bioinformatics

ISSN: 1471-2105

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