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Table 10 Summary of radius results extracted from CLSM by eight algorithms and compared to the reference radius measurements from SEM

From: Modeling, validation and verification of three-dimensional cell-scaffold contacts from terabyte-sized images

Fluorescent Input Radius ± stdev Estimate [um] Number of points
Algorithm ALL: Average ± stdev Internal: Average ± s tdev ALL Internal
A1 (stats: single pixel) 2.2795 ± 0.6151 2.3075 ± 0.7189 32,608 22,128
A2 (stats: mixed pixel) 1.1190 ± 0.3128 1.1562 ± 0.3464 32,608 22,128
A4 (stats: noise model) 2.6851 ± 1.3196 2.7745 ± 1.5440 32,608 22,128
A5 (stats: MRF) 1.7532 ± 0.3353 1.7648 ± 0.3843 32,608 22,128
A6 (geom: σ= 1.0) 1.1139 ± 0.1960 1.0815 ± 0.2112 36,249 25,709
A7 (geom: σ= 1.5) 1.6251 ± 0.1065 1.6136 ± 0.1175 30,105 20,064
A8 (geom: thresh) 2.0404 ± 0.3567 2.0674 ± 0.4018 32,138 21,691
SEM Input Average Radius: 1.1242 ± 0.075 Number of points: 104,341