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Table 1 Comparative results of simulated IS obtained from different tools

From: VISPA2: a scalable pipeline for high-throughput identification and annotation of vector integration sites

TP 440 422 357 294 436
FP 0 0 50 1 11
FN 15 33 48 160 8
  1. A dataset of 455 simulated IS generated previously [22] was used to test the performance of VISPA2 and other available IS mapping tools. In the confusion matrix used to assess precision and recall we defined: TP True Positives, number of IS correctly mapped into the genome (with a tolerance of 3 bp); FP False Positives, number of IS mapped in a wrong genomic location (>3 bp from the theoretical locus); FN False Negatives, number of discarded IS