Table 2 Target proteins of the used datasets regarding treatments with Dexamethasone (Dex), or Ethanol (EtOH), or with no treatment (None)
From: Explorative visual analytics on interval-based genomic data and their metadata
# | Target protein | Antibody target | Associated disease (main) | Dex | EtOH | None |
|---|---|---|---|---|---|---|
1 | Activating Transcription Factor 3 | ATF3 | Hodgkin’s lymphoma [38] | ✓ | ||
2 | B-cell lymphoma 3 | BCL3 | Lymphoma and chronic lymphocytic leukemia [39] | ✓ | ||
3 | Transcriptional repressor CTCF | CTCF | Regulation of chromatin architecture [40] | ✓ | ✓ | |
4 | E1A binding protein p300 | EP300 | Rubinstein-Taybi syndrome [41] | ✓ | ||
5 | Forkhead box protein A1 | FOXA1 | Estrogen receptor α (ER α) breast cancer [42] | ✓ | ||
6 | GA-binding protein alpha chain | GABPA | Down syndrome [43] | ✓ | ||
7 | Transcription factor jun-B | JUNB | Myeloproliferative disorder [44] | ✓ | ||
8 | Transcription factor jun-D | JUND | Adult-T cell leukaemia [45] | ✓ | ||
9 | Glucocorticoid receptor | NR3C1 | Glucocorticoid resistance syndrome [46] | ✓ | ||
10 | Pre-B-cell leukemia transcription factor 3 | PBX3 | Pilocytic astrocytoma [47] | ✓ | ||
11 | DNA-directed RNA polymerase II subunit RPB1 | POLR2A | UV-sensitive syndrome [48] | ✓ | ✓ | |
12 | Double-strand-break repair protein rad21 homolog | RAD21 | Cornelia de Lange syndrome [49] | ✓ | ||
13 | RE1-silencing transcription factor | REST | Wilms tumor [50] | ✓ | ||
14 | Paired amphipathic helix protein Sin3a | SIN3A | Chromosome 15q24 microdeletion syndrome [51] | ✓ | ||
15 | Homeobox protein SIX5 | SIX5 | Branchio-oto-renal syndrome [52] | ✓ | ||
16 | Transcription initiation factor TFIID subunit 1 | TAF1 | X-linked dystonia-parkinsonism [53] | ✓ | ||
17 | Transcription factor 12 | TCF12 | Extraskeletal myxoid chondrosarcoma [54] | ✓ | ||
18 | Transcriptional enhancer factor TEF-3 | TEAD4 | Narcolepsy [55] | ✓ | ||
19 | Upstream stimulatory factor 1 | USF1 | Hyperlipidemia [56] | ✓ | ✓ |