Table 5 Significant GO Terms and KEGG Pathways for EC-MTG regions pair
Sl No | Module name | Aggregated rank | Module size | GO term | GO ID | p-Value | KEGG pathway | p-Value |
|---|---|---|---|---|---|---|---|---|
1 | Coral1 | 5 | 35 | Positive regulation of dendrite extension | GO:1903861 | 3.10E-02 | Not found | NA |
2 | Darkolivegreen | 6 | 55 | Cytoskeleton-dependent intracellular transport | GO:0030705 | 5.60E-04 | Alzheimer’s disease | 9.20E-05 |
3 | Ivory | 4 | 49 | Not found | NA | NA | Not found | NA |
4 | Lightcyan | 3 | 76 | Regulation of translational initiation | GO:0006446 | 6.00E-03 | GnRH signaling pathway | 2.80E-02 |
5 | Mediumorchid | 8 | 32 | Cytoskeleton organization | GO:0007010 | 1.50E-03 | Dorso-ventral axis formation | 3.50E-02 |
6 | Navajowhite2 | 2 | 38 | Response to peptide hormone | GO:0043434 | 8.10E-02 | Not found | NA |
7 | Paleturquoise | 7 | 58 | Positive regulation by host of viral transcription | GO:0043923 | 3.30E-02 | Glyoxylate and dicarboxylate metabolism | 6.10E-02 |
8 | Plum1 | 1 | 53 | Dentate gyrus development | GO:0021542 | 3.40E-02 | Not found | NA |
9 | Purple | 10 | 99 | Double-strand break repair via nonhomologous end joining | GO:0006303 | 1.50E-04 | Endocrine and other factor-regulated calcium reabsorption | 2.50E-03 |
10 | Salmon | 9 | 85 | Glycolytic process | GO:0006096 | 8.90E-05 | Metabolic pathways | 1.90E-04 |
11 | Antiquewhite4 | 57 | 34 | ion transmembrane transport | GO:0034220 | 3.90E-02 | Alzheimer’s disease | 4.20E-03 |
12 | Blue | 60 | 137 | Protein transport | GO:0015031 | 1.30E-02 | Peroxisome | 5.90E-02 |
13 | Brown4 | 65 | 46 | Cilium morphogenesis | GO:0060271 | 2.60E-03 | Not found | NA |
14 | Cyan | 63 | 80 | Regulation of meiotic nuclear division | GO:0040020 | 1.70E-02 | Ras signaling pathway | 4.20E-02 |
15 | Darkgrey | 61 | 66 | Pyruvate biosynthetic process | GO:0042866 | 1.60E-02 | Biosynthesis of amino acids | 2.50E-02 |
16 | Darkmagenta | 59 | 55 | Antigen processing and presentation of exogenous peptide antigen via MHC class I: TAP-dependent | GO:0002479 | 8.00E-03 | Parkinson’s disease | 3.20E-02 |
17 | Darkseagreen4 | 62 | 35 | Glomerulus development | GO:0032835 | 1.30E-02 | SNARE interactions in vesicular transport | 7.60E-02 |
18 | Greenyellow | 64 | 94 | Regulation of synaptic vesicle recycling | GO:1903421 | 1.20E-02 | Alzheimer’s disease | 3.20E-02 |
19 | Lightsteelblue1 | 58 | 52 | Positive regulation of gene expression | GO:0010628 | 2.60E-02 | Calcium signaling pathway | 1.20E-02 |
20 | Yellow | 56 | 130 | Protein localization to plasma membrane raft | GO:0044860 | 1.20E-02 | Endocytosis | 1.70E-02 |