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Table 2 The betweenness degrees of proteins in the identified subnetwork

From: The node-weighted Steiner tree approach to identify elements of cancer-related signaling pathways

Protein

Betweenness

Protein

Betweenness

Protein

Betweenness

AKT1

112

PDGFR β

14

LEF1

8

PIK3R1

112

IGF1R

14

TCF7L1

8

p53

64

ERBB2

14

BAD

8

MDM2

64

INSRR

14

Caspase9

8

EP300

56

FGFR1

14

TCF7

8

HER1

56

FGFR2

14

mTOR

8

Grb2

42

I κ B α

8

AR

8

β -catenin

40

NF- κB

8

FOXO1

8

RELA

16

p27

8

TCF7L2

8

PDGFR α

14

p21

8

  
  1. The bold font is used to highlight the identified important proteins of PI3K/Akt and MAPK signaling pathways