Fig. 3
From: Cell type discovery and representation in the era of high-content single cell phenotyping
Cell type clustering and marker gene expression from RNA sequencing of single nuclei isolated from layer 1 cortex of post-mortem human brain. a Heatmap of CPM expression levels of a subset of genes that show selective expression in the 11 clusters of cells identified by principle component analysis (not show). An example of the statistical methods used to identify cell clusters and marker genes from single cell/single nuclei data can be found in [13]. b Violin plots of selected marker genes in each of the 11 cell clusters. c The expanded is_a hierarchy of the neuron branch of the Cell Ontology, with the interneuron sub-branch highlighted