Fig. 4
From: Redundancy analysis allows improved detection of methylation changes in large genomic regions
RDA biplot of the HER2 region (BRCA dataset) using HER2 and ER sample status. The adjusted model also includes surrogate variables in the analysis. The points represent the samples and are coloured according to the combination of HER2 and ER status. ER-, ER+, HER- and HER+ labels are placed at the centroid of their respective groups. The CpGs most associated with the RDA components are represented with labels. R2 is the proportion of variance in methylation data explained by the model. The p-value of the RDA model was computed by sampling the HER2 and ER sample status variables