Fig. 4
From: Simulating autosomal genotypes with realistic linkage disequilibrium and a spiked-in genetic effect

Comparison of minor allele frequencies (MAFs) in the original data versus those in a single simulated data set. The red crosses represent the SNPs with MAF in the simulated data that fall outside 95% binomial prediction intervals calculated using the SNP’s MAF in the original data as its true MAF (4.9% of the SNPs are in this category)