Table 3 The feature subset combined the features selected by decision tree and mRMR

BsRASA

Bound side-chain relative accessible surface area

UsASA

Unbound side-chain accessible surface area

DpRASA ^1/2

\( {\left({RASA}_{unb}(polar)-{RASA}_{bnd}(polar)\right)}^{\frac{1}{2}} \)

BsmDI

Bound side-chain mean depth index

Conservation

Conservation

UpRASA

Unbound polar relative accessible surface area

CNSV_REL1

\( CNSV\_ REL1=\frac{{\widehat{P}}_{ra}}{{\widehat{P}}_A} \)

DtASA ^1/2

\( {\left({ASA}_{unb}(total)-{ASA}_{bnd}(total)\right)}^{\frac{1}{2}} \)

UpASA

Unbound polar accessible surface area

UtmDI

Unbound total mean depth index

Hdrpo

Hydrophobicity

BtRASA

Bound total relative accessible surface area

B factor

Temperature factor

Hdrpi

Hydrophilicity

BminPI

Bound minimal protrusion index

DnASA ^5/2

\( {\left({ASA}_{unb}\left( non- polar\right)-{ASA}_{bnd}\left( non- polar\right)\right)}^{\frac{5}{2}} \)

BpRASA

Bound polar relative accessible surface area

BtmDI

Bound total mean depth index

BsASA

Bound side-chain accessible surface area

DtASA ^3/2

\( {\left({ASA}_{unb}(total)-{ASA}_{bnd}(total)\right)}^{\frac{3}{2}} \)