Protein-protein interface hot spots prediction based on a hybrid feature selection strategy

BMC Bioinformatics

Table 5 Statistical performance of our model for predicting hotspot of the independent test set by types of amino acids

Types of residues	Accuracy	Specificity	Recall	Precision	F-measure
All residues (28 HS/ 67 NS)	0.705	0.657	0.821	0.500	0.621
Charged residues^a (13 HS/ 28 NS)	0.732	0.750	0.692	0.563	0.621
Non Charged residues	0.685	0.590	0.933	0.467	0.622
Polar residues^b (14 HS/41 NS)	0.709	0.707	0.714	0.455	0.556
Non polar residues	0.700	0.577	0.929	0.542	0.685
Aromatic residues^c (11 HS/12 NS)	0.652	0.417	0.818	0.563	0.667
Non aromatic residues	0.736	0.709	0.824	0.467	0.596

ISSN: 1471-2105