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Fig. 11 | BMC Bioinformatics

Fig. 11

From: HiComet: a high-throughput comet analysis tool for large-scale DNA damage assessment

Fig. 11

Comets and their heads. Green images represent comets, on which red circles indicate the location of the head, as manually determined by domain experts. The four images represent different states, as follows: a normal, b necrosis, and c and d apoptosis. For a and b, the head diameters are similar to the comet heights. In contrast, the head diameter is smaller than the comet heights in c and d. CometScore (TriTek Corp., Sumerduck, VA) does not consider this fact and tends to overestimate the head diameter, resulting in an underestimation of the tail moment. More details of c and d are listed in Table 3

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