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Table 1 Explanation of all individual techniques used to predict drug AUC. Methods utilizing Residuals predict the sample-mean centered sensitivities (actual AUC- mean AUC) instead of the AUC directly

From: Investigation of model stacking for drug sensitivity prediction

Method

Description

Mean

Prediction using the mean AUC of each drug

KNN Direct

K Nearest Neighbor (KNN) Approach using the actual AUC with drug target data

KNN Residual

KNN using the residuals with drug target data

NN GE

Neural Network on Gene Expressions

NN Phy Direct

Neural Network on Chemical Descriptors of drugs

RF Phy Residual

Random Forest on Chemical Descriptors of drugs using the residuals

RF GE

Random Forest on Gene expression