Fig. 1

Anatomy of a ToxPi profile. Profiles for two example chemicals (simulated data) are shown for a model combining source data into 7 slices. For each slice, the distance that the arc extends from the origin is proportional to its relative evidence of concern (e.g. longer = greater risk), and the radial angle (width) indicates its weight in the overall model. The optional confidence intervals (upper and lower 95%) are indicated as the lighter-shaded area at the boundary of each slice arc. The inner circle indicates the percentage of missing data (darker = higher missingness) in each slice. In this example, the profile on the left has a higher overall priority score (and would be ranked higher in the distributional rank plot in Fig. 2) than the profile on the right