Fig. 4

Matrix view for the exploration and filtering of the input configurations. a Matrix view showing the aggregated information about the presence of mutually interacting amino acids in all configurations. Horizontal and vertical axes contain the lists of amino acids in the contact zones of the interacting proteins P₁ and P₂. b The side view shows individual configurations sorted according to their similarity to the primary configuration. The interaction with the side view enables to gain more detailed information about the configurations and their interacting amino acids. The central part of the side view consists of a scrollable list of individual configurations. The vertical list of amino acids (the rightmost column) is the same list as the one on the horizontal axis. The configuration in focus contains one polyline connecting those two amino acids from the contact zone which are the closest ones (red lines). The remaining interactions between amino acids are marked with black polylines. The green borders of some matrix cells represent the pairs which are present in the configuration selected in the side view. The selected cells are marked with a cross. It is possible to enlarge a selected row and column using an interactive lens