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Table 2 Individuals with discordant HER2 (IHC) status and level, not measured by FISH (individuals not expressing ER and PR, and without a FISH classification are highlighted in bold)

From: Ensemble outlier detection and gene selection in triple-negative breast cancer data

Individual ER PR HER2 HER2 level (IHC) HER2 status (IHC) Type
TCGA-AC-A8OS 94.72(+) 1.14(+) 23.55 1+ + non-TNBC
TCGA-LL-A73Y 0.22(-) 0.18(-) 19.00 3+ - TNBC
TCGA-AN-A0FL 0.09 (-) 1.7(-) 15.07 1+ + non-TNBC
TCGA-AN-A0FX 1.13(-) 0.64(-) 24.02 1+ + non-TNBC
TCGA-AN-A0FK 128.26(+) 31.59(+) 25.62 1+ + non-TNBC
TCGA-E9-A295 17.36(+) 6.80(+) 34.83 1+ + non-TNBC
TCGA-AC-A3YI 5.65(+) 0.76(+) 60.87 1+ + non-TNBC
TCGA-JL-A3YW 0.35(+) 0.09(+) 31.47 1+ + non-TNBC
TCGA-AN-A0FS 91.87(+) 1.16(-) 43.92 1+ + non-TNBC
TCGA-AN-A0FN 21.34(+) 1.14(+) 17.50 1+ + non-TNBC
TCGA-AN-A0FJ 0.08(+) 0.04(-) 14.28 1+ + non-TNBC
TCGA-AC-A3W6 28.89(+) 0.26(+) 19.24 3+ - non-TNBC
TCGA-AN-A03X 0.75(+) 12.28(+) 38.03 1+ + non-TNBC
  1. Individuals marked with asterisks show no concordance regarding HER2 labeling by different testing and are misclassified by logistic regression based on the 3 variables clinically used to classify breast cancer patients into TNBC