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Table 2 Individuals with discordant HER2 (IHC) status and level, not measured by FISH (individuals not expressing ER and PR, and without a FISH classification are highlighted in bold)

From: Ensemble outlier detection and gene selection in triple-negative breast cancer data

Individual

ER

PR

HER2

HER2 level (IHC)

HER2 status (IHC)

Type

TCGA-AC-A8OS

94.72(+)

1.14(+)

23.55

1+

+

non-TNBC

TCGA-LL-A73Y

0.22(-)

0.18(-)

19.00

3+

-

TNBC

TCGA-AN-A0FL

0.09 (-)

1.7(-)

15.07

1+

+

non-TNBC

TCGA-AN-A0FX

1.13(-)

0.64(-)

24.02

1+

+

non-TNBC

TCGA-AN-A0FK

128.26(+)

31.59(+)

25.62

1+

+

non-TNBC

TCGA-E9-A295

17.36(+)

6.80(+)

34.83

1+

+

non-TNBC

TCGA-AC-A3YI

5.65(+)

0.76(+)

60.87

1+

+

non-TNBC

TCGA-JL-A3YW

0.35(+)

0.09(+)

31.47

1+

+

non-TNBC

TCGA-AN-A0FS

91.87(+)

1.16(-)

43.92

1+

+

non-TNBC

TCGA-AN-A0FN

21.34(+)

1.14(+)

17.50

1+

+

non-TNBC

TCGA-AN-A0FJ

0.08(+)

0.04(-)

14.28

1+

+

non-TNBC

TCGA-AC-A3W6

28.89(+)

0.26(+)

19.24

3+

-

non-TNBC

TCGA-AN-A03X

0.75(+)

12.28(+)

38.03

1+

+

non-TNBC

  1. Individuals marked with asterisks show no concordance regarding HER2 labeling by different testing and are misclassified by logistic regression based on the 3 variables clinically used to classify breast cancer patients into TNBC