Fig. 2From: Sequence-based prediction of physicochemical interactions at protein functional sites using a function-and-interaction-annotated domain profile databaseMapping known protein function sites and interactions to a domain-profile module, ⊗: known PFSs of domain structures, ⊙: pivotal PFSs in a profile module with the number indicating a weight factor, *: PFSs mapped into the query protein sequence from profile module pivotal sites, which, after a filtering, is reduced to two points (A and B) as a final prediction output, Δ: non-conservative pivotal sites mapped into the query protein, which will be ignored due to the low conservation valueBack to article page