Fig. 1From: Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression dataStudy Workflow. Eight network reconstruction methods – including five general methods: partial correlation (Pcorr), Bayesian network (BN), GENIE3, ARACNE and CLR, and three single cell-specific methods: SCENIC, SCODE and PIDC – were applied to two single cell experimental datasets, and two simulated datasets that resemble single cell data. Evaluation of these methods was based on their ability to reconstruct a reference network, and this was assessed using PR, ROC curves, and other network analysis metricsBack to article page