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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data

Fig. 1

Study Workflow. Eight network reconstruction methods – including five general methods: partial correlation (Pcorr), Bayesian network (BN), GENIE3, ARACNE and CLR, and three single cell-specific methods: SCENIC, SCODE and PIDC – were applied to two single cell experimental datasets, and two simulated datasets that resemble single cell data. Evaluation of these methods was based on their ability to reconstruct a reference network, and this was assessed using PR, ROC curves, and other network analysis metrics

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