Fig. 4

AUROC (top) and AUPR (bottom) scores demonstrate consistently poor performance for most of the methods and datasets. In both panels, the horizontal red lines represent the line of a random guess and baseline, which are the same (= 0.5) for AUROC across datasets (a) but differ for AUPR (b), since the baseline indicates the value of precision when all the reference edges were recovered, and this depends on the total number of genes in the datasets and the number of edges in the reference networks