Predicting drug-disease associations by using similarity constrained matrix factorization

BMC Bioinformatics

Table 6 Top 10 predicted diseases associated with Clozapine

Index	Disease Name	Disease ID	Score	Evidence
1	Sleep Initiation and Maintenance Disorders	D007319	1	https://en.wikipedia.org/wiki/Clozapine
2	Anxiety Disorders	D001008	0.9117	N.A.
3	Inappropriate ADH Syndrome	D007177	0.7434	A Case report [41]
4	Stress Disorders, Post-Traumatic	D013313	0.7267	Report [42, 43]
5	Parkinson Disease, Secondary	D010302	0.7179	Review [44]
6	Memory Disorders	D008569	0.7123	An animal study [45]
7	Status Epilepticus	D013226	0.6312	https://en.wikipedia.org/wiki/Clozapine
8	Headache	D006261	0.6166	https://en.wikipedia.org/wiki/Clozapine
9	Torsades de Pointes	D016171	0.5953	N.A.
10	Attention Deficit Disorder with Hyperactivity	D001289	0.5913	N.A.

ISSN: 1471-2105