Drug response prediction model using a hierarchical structural component modeling method

BMC Bioinformatics

Table 4 AUC score comparison between HisCoM, GLM, and GLMwR drug response models using triple candidate proteins

Protein	HisCoM	GLM	GLMwR
APOC4_CD163_CD5L	0.920	0.883	0.920
APOC4_CD163_SERPING1	0.880	0.886	0.877
APOC4_CD163_JCHAIN	0.917	0.894	0.914
APOC4_CD163_RBP4	0.886	0.866	0.874
APOC4_CD5L_SERPING1	0.920	0.937	0.931
APOC4_CD5L_JCHAIN	0.920	0.891	0.926
APOC4_CD5L_RBP4	0.897	0.886	0.906
APOC4_SERPING1_JCHAIN	0.946	0.960	0.943
APOC4_SERPING1_RBP4	0.877	0.863	0.869
APOC4_JCHAIN_RBP4	0.920	0.866	0.929
CD163_CD5L_SERPING1	0.940	0.923	0.949
CD163_CD5L_JCHAIN	0.869	0.929	0.914
CD163_CD5L_RBP4	0.951	0.943	0.949
CD163_SERPING1_JCHAIN	0.957	0.957	0.954
CD163_SERPING1_RBP4	0.923	0.929	0.911
CD163_JCHAIN_RBP4	0.954	0.909	0.954
CD5L_SERPING1_JCHAIN	0.923	0.937	0.940
CD5L_SERPING1_RBP4	0.946	0.957	0.949
CD5L_JCHAIN_RBP4	0.943	0.937	0.940
SERPING1_JCHAIN_RBP4	0.946	0.943	0.943

ISSN: 1471-2105