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Table 6 Simulation study 2 with nX=nY=30 and 100 runs

From: Identification of differentially expressed genes by means of outlier detection

Number of

 

1 block

2 blocks

DE genes

 

α

α

per block

 

0.1

0.05

0.01

0.1

0.05

0.01

5

\(\hat {p}_{m}\)

0

0

0

0

0

0

 

%

100 (0)

100 (0)

100 (0)

100 (0)

100 (0)

100 (0)

20

\(\hat {p}_{m}\)

0

0

0

0

0

0

 

%

100 (0)

100 (0)

100 (0)

100 (0)

100 (0)

100 (0)

100

\(\hat {p}_{m}\)

0

0

0

0

0

0

 

%

100 (0)

100 (0)

100 (0)

100 (0)

100 (0)

100 (0)

Number of

 

3 blocks

   

DE genes

 

α

   

per block

 

0.1

0.05

0.01

   

5

\(\hat {p}_{m}\)

0

0

0

   
 

%

100 (0)

100 (0)

100 (0)

   

20

\(\hat {p}_{m}\)

0

0

0.01

   
 

%

100

100

99.9 (0.7)

   

100

\(\hat {p}_{m}\)

0

0.01

0.04

   
 

%

100 (0)

100.0 (0.0)

99.8 (1.9)

   
  1. Evaluation of the first step of the ORdensity method using different values of α. The Table shows the estimated probability, \(\hat {p}_{m}\), of no considering as a potential DE gene at least one gene that it really is, and the mean proportion of DE genes (row named “%”) that the procedure considered as potential DE genes. Corresponding standard deviations are in brackets