Table 2 21 selected targets based on network analysis
Target Name | Gene Symbol | Target Type | Be Enriched or Not | Betweenness Centrality |
|---|---|---|---|---|
Heat shock protein 90Â kDa alpha (cytosolic), class A member 1 | HSP90AA1 | Candidate | Yes | 0.04743 |
Epidermal growth factor receptor | EGFR | Candidate | Yes | 0.02710 |
Cyclin-dependent kinase 2 | CDK2 | Candidate | Yes | 0.01959 |
Albumin | ALB | Candidate | No | 0.01653 |
Glycogen synthase kinase 3 beta | GSK3B | Candidate | Yes | 0.01317 |
V-rel reticuloendotheliosis viral oncogene homolog A (avian) | RELA | Known | Yes | 0.00777 |
Mitogen-activated protein kinase 14 | MAPK14 | Candidate | Yes | 0.00765 |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | NFKB1 | Known | Yes | 0.00364 |
Dipeptidyl-peptidase 4 | DPP4 | Candidate | No | 0.00348 |
Mitogen-activated protein kinase 8 | MAPK8 | Candidate | Yes | 0.00321 |
Lymphocyte-specific protein tyrosine kinase | LCK | Candidate | Yes | 0.00279 |
Cyclin-dependent kinase 6 | CDK6 | Candidate | Yes | 0.00277 |
RAB5A, member RAS oncogene family | RAB5A | Candidate | No | 0.00275 |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | SERPINA1 | Candidate | No | 0.00244 |
Cathepsin B | CTSB | Candidate | No | 0.00241 |
Caspase 3, apoptosis-related cysteine peptidase | CASP3 | Known | Yes | 0.00238 |
K(lysine) acetyltransferase 2B | KAT2B | Candidate | No | 0.00237 |
Retinoic acid receptor, alpha | RARA | Known | Yes | 0.00198 |
Vascular endothelial growth factor A | VEGFA | Known | Yes | 0.00178 |
Caspase 8, apoptosis-related cysteine peptidase | CASP8 | Known | Yes | 0.00165 |
Retinoid X receptor, alpha | RXRA | Known | Yes | 0.00163 |