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Table 1 Top 3 significant associations between factors in mouse and human cell types

From: Insights into mammalian transcription control by systematic analysis of ChIP sequencing data

Cell type Combination 1 Combination 2 Combination 3
B cells (M) E2A, FoxO1, Pax5 E2A, Ebf1, Oct2 Pax5, Smad3, FoxO1A
T cells (M) Stat3, Stat4, Stat5, Stat6 Stat5a, Stat5b, Stat5 Fli1, Gata3
Dendritic cells (M) Hif1a, Irf1, Maff, Relb, Stat3, Rel, Irf2Irf4 Hif1a, Irf1, Maff, Relb, Rel, Irf2Irf4 -
Macrophages (M) CEBPA, CEBPB CEBPA, CEBPB, PU1, STAT1 CEBPA, CEBPB, PPARG, PU1, STAT1
Erythroid cells (M) ETO2, GATA1, LDB1, MTGR1, SCL GATA1, LDB1, MTGR1, SCL -
MK progenitors (M) CBFB, GATA1, GATA2, RING1B, RUNX1 CBFB, ETS1, RING1B, RUNX1 -
MEL (M) JunD, SMC3 GATA1, SCL CMYC, MAX, MXI1, NELFE, SCL, TBP
ES cells (M) Suz12, SOX2 E2F1, nMYC E2F1, KLF4, nMYC
A549 (H) HDAC6, P300, ELF1, ETS1, GABP ATF3, BRF1 RNA polII, CTCFL
GM12878 (H) SAP30, TAF7 STAT5A, BRG1 P300, ETS1
H1-hESC (H) RAD21, ZNF143 BACH1, MAFK USF1, USF2
HeLa-S3 (H) EZH2, RNA polII, SIN3A, CJUN, CMYC GTF2B, NR2F2 RNAPII, RBBP5
HepG2 (H) TAF1, TAF7, TEAD4 SAP30, ATF1, ATF3 PU1, STAT5A
K562 (H) GTF2F1, CTCF HDAC1, CJUN E2F6, CTCF
  1. All associations were predicted at very high significance (all P-values <1e-256). M - mouse, H - human