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Table 1 The number of the inferred compounds and inferred genes associated with significant dose-dependent activity

From: Drug candidate identification based on gene expression of treated cells using tensor decomposition-based unsupervised feature extraction for large-scale data

Cell lines BT20 HS578T MCF10A MCF7 MDAMB231 SKBR3
Tumour Breast      
Inferred genes 41 57 42 55 41 46
Inferred compounds 4 3 2 6 5 6
All compounds 110 106 106 108 108 106
Predicted targets 418 576 476 480 560 423
Cell lines A549 HCC515 HA1E HEPG2 HT29 PC3
Tumour   Lung Kidney Liver Colon Prostate
Inferred genes 45 46 48 54 50 63
Inferred compounds 8 5 7 2 2 9
All compounds 265 270 262 269 270 270
Predicted targets 428 352 423 396 358 439
Cell lines A375      
Tumour Melanoma      
Inferred genes 43      
Inferred compounds 6      
All compounds 269      
Predicted targets 421      
  1. The target genes predicted by means of the comparison with the data showing upregulation of the expression of individual genes (‘predicted targets’) are also shown. The full list of inferred genes and predicted targets is available in Additional file 7. Inferred compounds are presented in Table 2. ‘All compounds’ rows represent the total number of compounds used for the treatment of each cell line