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Table 5 Significant disease associated genes in the IL–17 family

From: Multi–omic analysis of signalling factors in inflammatory comorbidities

Disease

Up–regulated DEG

Down–regulated DEG

Up–regulated DMG

Down–regulated DMG

Allergy

Asthma

CFS

IL17A

Colitis

Colon Cancer

Crohn

IL17E

RA

SLE

IL17E

T2D

IL17F, IL17AIL17BIL17E

IL17C

  1. DEG stands for dysregulated expressed genes and DMG stands for dysregulated methylated genes. Genes in bold represent significant dysregulations according to both promoter methylation model and gene body methylation model; Genes in italic represent significant dysregulations according to promoter methylation model; Genes in normal fonts represent significant dysregulations according to gene body methylation model