ASGAL: aligning RNA-Seq data to a splicing graph to detect novel alternative splicing events

BMC Bioinformatics

Table 4 Quality measures in detecting novel alternative splicing events on the simulated datasets with 5M and 10M reads

Results obtained by ASGAL, SplAdder and rMATS (for which we used STAR to compute the alignments), and SUPPA2 (for which we used Salmon to obtain the transcript quantification) are reported. Precision (Prec), Recall (Rec), and F-Measure (FM) achieved on the simulated datasets in detecting novel alternative splicing events: exon skipping (ES), alternative acceptor site (A3), alternative donor site (A5), and intron retention (IR). A dash “-” means that the considered tool is not designed to detect that type of novel AS events

ISSN: 1471-2105