Table 8 Gene characteristics significant in stepwise best subset multiple linear regression model for nonsense mutations
From: Gene characteristics predicting missense, nonsense and frameshift mutations in tumor samples
Predictor | T-test | P-value | Beta (ß) |
|---|---|---|---|
Number of potential sites for nonsense mutations | 27.77 | 3.42 × 10−132 | 0.782 |
Number of silent mutations in the gene | 26.03 | 1.66 × 10− 129 | 0.301 |
Gene size in nucleotides | −16.22 | 5.10 × 10− 49 | − 0.498 |
Percentage of “G” | − 3.07 | 4.60 × 10− 4 | − 0.028 |
Replication time | −2.35 | 7.10 × 10− 3 | − 0.021 |
Evolutionary conservation | 2.23 | 2.26 × 10− 2 | 0.016 |