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Table 1 The distribution of single mutant amino acids for the four datasets

From: dbMPIKT: a database of kinetic and thermodynamic mutant protein interactions

Dataset

Amino acid

SKEMPI

BID

AB-Bind

dbMPIKT

Total

Hydrophobic

A

1057

256

267

673

2253

I

53

0

2

11

66

L

77

0

3

17

97

M

60

0

3

12

75

V

74

0

12

12

98

W

5

0

14

13

81

Y

56

0

14

14

84

F

94

0

8

23

125

S

71

0

11

21

103

Polar

T

48

0

6

9

63

N

60

0

15

21

96

Q

78

0

25

21

124

Positive

R

76

0

15

18

109

K

98

0

7

29

134

H

54

0

2

10

66

Negative

D

76

0

15

27

118

E

83

0

12

35

130

Other

C

45

0

1

14

60

G

59

0

7

21

87

P

78

0

25

21

124

Total

 

2316

256

440

1010

4022