Fig. 5

Major influential factors for regulating INS expression. a Correlation and mutual information between INS expression and the three factors. OXID, ER and CASP denote oxidative stress, ER stress and death executioner caspases, respectively. b INS expression in T2D β-cells in the scenarios of low (L), medium (M) and high (H) levels of oxidative stress. The dark horizontal short lines mark the median values. The percentage of difference between two groups is provided in the figure. The symbol of * in both A and B indicates that p-value < 0.05