Table 4 Functional homogeneity of mesoscale modules detected by Louvain algorithm, evaluated using three ontologies: MF, BP, and CC
From: Functional homogeneity and specificity of topological modules in human proteome
PPIN | MF | BP | CC | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
max | mean | std | max | mean | std | max | mean | std | ||
Physical | Binary | 0.81 | 0.79 | 0.01 | 0.85 | 0.59 | 0.24 | 0.78 | 0.75 | 0.04 |
Weighted | 0.83 | 0.80 | 0.02 | 0.75 | 0.42 | 0.31 | 0.80 | 0.77 | 0.01 | |
Functional | Binary | 0.71 | 0.64 | 0.12 | 0.72 | 0.57 | 0.25 | 0.8 | 0.72 | 0.25 |
Weighted | 0.71 | 0.42 | 0.22 | 0.74 | 0.60 | 0.25 | 0.8 | 0.76 | 0.07 | |
Combined | Binary | 0.74 | 0.73 | 0.01 | 0.70 | 0.58 | 0.25 | 0.77 | 0.75 | 0.01 |
Weighted | 0.73 | 0.72 | 0.002 | 0.72 | 0.45 | 0.29 | 0.76 | 0.75 | 0.01 | |