Table 1 Performance of pRANK and AMYCO approaches in the prediction of mutation impact upon the aggregation of the human prion-like protein hnRNPA2

Sensitivity

0

1

Specificity

1

1

Precision

–

1

Accuracy

0.45

1

MCC

–

1

Mean % error

−7.08

−1.25

Standard Deviation (%)

37.71

12.19

SEM (%)

8.04

2.44

Coefficient of Determination

0.152

0.882

P-value (two tailed test)

0.468

< 1.00E-08

Rho (ρ)

0.334

0.929