  
FastCC

ExtraFastCC


Model

# reacts

# rev dead reacts

# LPs

time / s

# LPs

time / s


iTO977

1536

120

215

8.0

6

0.8

iJO1366

2583

241

489

27.2

6

9.0

Recon1

3719

395

794

117.6

21

7.9

 Disconnected reaction/metabolite clusters were discarded from every model before the testing in order to avoid unrealistically large LP numbers caused by running LPs on many small clusters. The first column shows the model name, the second shows the number of reactions in the model, and the third shows the number of blocked reversible reactions in the model. The numbers of reactions are recorded after disconnectedcluster purging. Note that the number of LPs used by FastCC is approximately equal to twice the number of dead reversible reactions. ExtraFastCC uses the open source solver Clp, while FastCC is run in Matlab using the much faster Gurobi [27] solver